Formulation of Film Coated Tablets of Norfloxacin and Tinidazole by Anilkumar Shinde, Harinath More (Paperback, 2018)

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However it has been shown that film coating technology economical & useful in masking the taste. & 100% release in 30 min. For all tablet formulation drug release at the end of 30 min was found in the range of 52.78±0.09 to 100.07±0.5 % and from the obtained results, F-07 was selected as an optimized formulation for designing palatable tablet.

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The aim of the present study was development and optimization of an efficacious, pharmaco-economical, palatable and marketable film coated tablet formulation of Norfloxacin-Tinidazole. Bitter taste of both drugs reduces the patient compliance & hence marketability. However it has been shown that film coating technology economical & useful in masking the taste. The core tablets with maximum hardness & minimum disintegration time were selected for film coating. (F-1 & F-07) The optimized formulation F-07 showed hardness, friability, disintegration time and drug release in range 9 kg/cm2, 0.17+/-0.02%, 27.40+/-2.1 sec. & 100% release in 30 min. respectively. For all tablet formulation drug release at the end of 30 min was found in the range of 52.78+/-0.09 to 100.07+/-0.5 % and from the obtained results, F-07 was selected as an optimized formulation for designing palatable tablet. Therefore it can be concluded that the present work discusses in depth the development and optimization of an efficacious, pharmaco-economical, palatable and marketable tablet formulation of Norfloxacin and Tinidazole.

Product Identifiers

PublisherLap Lambert Academic Publishing
ISBN-139786139977369
eBay Product ID (ePID)12049027927

Product Key Features

Publication Year2018
SubjectMedicine
Number of Pages96 Pages
LanguageEnglish
Publication NameFormulation of Film Coated Tablets of Norfloxacin and Tinidazole
TypeTextbook
AuthorAnilkumar Shinde, Harinath more
FormatPaperback

Dimensions

Item Height229 mm
Item Weight150 g
Item Width152 mm

Additional Product Features

Title_AuthorAnilkumar Shinde, Harinath more

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